Hypertensive patients with progressive cerebral small vessel disease have increased cognitive impairment

first_imgReviewed by James Ives, M.Psych. (Editor)Jan 4 2019Patients with high blood pressure and progression of periventricular white matter hyperintensities showed signs of cognitive impairment despite taking medication to lower their blood pressure, according to new research in the American Heart Association’s journal Hypertension.High blood pressure has been linked to an increased risk for dementia, but what’s unclear is what kinds of subtle negative changes take place in the brain that may affect cognitive function. Finding new ways to detect minor types of cognitive impairment may help determine who is at risk for early-stage dementia.In this study, researchers looked at 345 men and women with a median age of 65 who had high blood pressure. Patients underwent brain imaging scans, were tested in cognitive function areas including execution, memory and attention, and were followed for about four years. Patients’ average blood pressure during follow-up was 144.5/76.5 mm Hg. The American Heart Association/American College of Cardiology 2017 hypertension guidelines revised the definition of hypertension and classified it as a blood pressure reading of 130/80 mm Hg instead of 140/90.To understand what was going on in the brain, researchers looked at the brain’s white matter. White matter is important because it connects different regions of the brain, serving as a kind of infrastructure. Specifically, researchers looked at periventricular white matter, located in the central part of the brain. Periventricular white matter acts as a bridge between distant brain regions and serves an important role in cognitive function. Lesions or abnormalities found in periventricular white matter could signal cognitive impairment.Related StoriesNew therapy shows promise in preventing brain damage after traumatic brain injuryRush University Medical Center offers new FDA-approved treatment for brain aneurysmsStroke should be treated 15 minutes earlier to save lives, study suggestsDuring the study, 9 percent of the group developed mild cognitive impairment which may increase the risk for dementia. There was also a connection for periventricular white matter changes and the risk of mild cognitive impairment. Researchers found that patients with a progression of periventricular white matter abnormalities showed a six-fold increased risk of mild cognitive decline.The study observed that the progression of periventricular white matter abnormalities aligned with cognitive decline in global and executive function; small vessel bleeding in the brain was found to be related to a decline in attention.Although the development of brain lesions may be considered “silent” conditions in which patients do not feel or are unaware of symptoms, if left untreated, the risks of more severe forms of cognitive decline may increase. Researchers say more study is needed to better understand how periventricular white matter changes triggers cognitive decline.”The brain is an organ exposed to a high volume of blood flow and it is very vulnerable to sustained high blood pressure levels, and this might be happening silently or with mild symptoms, but that doesn’t mean there aren’t consequences,” said lead author Joan Jiménez Balado, Ph.D. student, Psychologist, M.Sc. in Neuroscience at the Institut de Recerca Hospital Vall d’Hebron in Barcelona, Spain. “High blood pressure and its consequences are really ‘covert’ diseases that tend to progress if it is not well managed.”Source: https://newsroom.heart.org/news/cognitive-impairment-risk-increased-in-hypertensive-patients-with-progressive-cerebral-small-vessel-disease?preview=35c4last_img read more

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Mice transmit brain benefits of enriched upbringing to nonenriched offspring

first_imgRelated StoriesBrain stimulation accelerates visual learning and recoveryNovel measures of PD-related brain activity detected with scalp electroencephalographyResearchers identify brain network that determines robot likabilityBlocking visual input to one eye of adult mice leads to a rewiring of the visual cortex to prioritize input from the open eye. Siegrid Löwel and colleagues first confirmed that this plasticity declines over time in mice housed in standard cages while it is preserved throughout life in mice raised in an enriched environment — in this case a large, two-story cage with separate living and eating areas connected by a ladder, regularly changed mazes, and a slide.The researchers then bred the mice to create three experimental groups of offspring, all of which were raised in standard cages. Despite being raised in the same impoverished environment, mice whose parents — particularly mothers — were raised in the enriched environment maintained lifelong plasticity in the visual cortex. These findings emphasize the importance of documenting rearing conditions of experimental animals across generations.Source: http://www.sfn.org/ Jan 22 2019Mice growing up in a basic cage maintain lifelong visual cortex plasticity if their parents were raised in an environment that promoted social interaction and physical and mental stimulation, according to a multigenerational study published in eNeuro. The research suggests life experience may be transmitted from one generation to the next through a combination of changes in gene expression and parental caretaking behavior.last_img read more

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New technology for machine translation now available

first_imgCredit: CC0 Public Domain Provided by Netherlands Organisation for Scientific Research (NWO) https://www.nwo.nl/onderzoek-en-resultaten/programmas/open+technologieprogramma/projecten/2012/2012-12271 The methodology is used in the application Matching Data, offered by TAUS, an important think tank in the field of machine translation. This application tackles a big challenge within digital translation: for a good translation it is necessary to train the translation machine with reliable sources and datasets that contain the relevant type of words. For example, translating a legal text requires a completely different vocabulary and a different type of translation than for example, a newspaper report.Successful implementationIn 2013 the DatAptor project, supervised by Professor Khalil Sima’an of the UvA Institute for Logic, Language and Computation, received funding from Technology foundation STW (now: NWO Domain Applied and Engineering Sciences) to deal with this problem. The research results of the DatAptor project have now been successfully implemented by think tank TAUS. They offer the new technology under the name Matching Data.On the weblog of TAUS Sima’an says: “Our dream was to make the world wide web itself the source of all data selections. But we decided to start more modest and make the very large TAUS Data repository our hunting field first. In DatAptor we learned that every domain is a mixture of many subdomains. The combinatorics of subdomains in a very large repository harbors a wealth of new, untapped selections. Therefore, if the user provides a Query corpus representing their domain of interest, the Matching Data method is likely to find a suitable selection in the repository.” More information: Data-Powered Domain-Specific Translation Services On Demand (DatAptor) Google moves to curb gender bias in translation This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. A new methodology to improve machine translation has become available this month through the University of Amsterdam. The project DatAptor, funded by NWO/STW, increasingly advances translation machines by selecting data sets. Citation: New technology for machine translation now available (2019, January 22) retrieved 17 July 2019 from https://phys.org/news/2019-01-technology-machine.html Explore furtherlast_img read more

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University informed of Nigerian students death

first_img Related News Related News Volume 90%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9 facebook twitter Email Linkhttps://www.thestar.com.my/news/nation/2019/07/13/university-informed-of-nigerian-students-death/?jwsource=clCopied EmbedCopiedLive00:0001:2401:24  Nation 17h ago Wisma Putra: No protest outside Malaysian High Comm in Nigeria Ewansiha was pursuing his PhD in Management, and was married with two children.The university described Ewan­siha as a member of its postgraduate centre.“He was an inspired young man. We offer our condolences to his family and many close friends.“We have no further information at this time. We are grateful for calm and understanding during this difficult time,” said the university.At a press conference yesterday, Limkokwing University of Creative Technology vice-chancellor Prof K. Ramanathan told reporters that everything was under control at the campus in Cyberjaya.“We took precautions but there were no untoward incidents,” he said, expressing his condolences to the family.Expressing its sympathies, the Education Ministry said it was confident that the authorities were conducting a thorough investigation into the death of the student. The ministry, it said in a statement, would be in touch with the Home Ministry for updates on the case. Nation 11h ago Education Malaysia Global Services expresses regret over death of Nigerian student Nation 20h ago Limkokwing confirms PhD student died in custody PETALING JAYA: Limkokwing University of Creative Technology was informed of its student Thomas Orhions Ewansiha’s death on Thursday.A member of the Nigerian High Commission requested for his student records at 11.33am on Thursday to confirm his identity and for visa status verification.“We immediately responded by making all files available to the embassy.“To our knowledge, Thomas (Ewansiha) was detained on July 5 at a public place in Kuala Lumpur during a raid,” the university said in a statement. {{category}} {{time}} {{title}}last_img read more

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Nataka in Karnataka Rahul Gandhi breaks his silence says BJP using money

first_imgOther Videos from India 26:36 Sat, 13 Jul, 2019 20 Years of Kargil: A ground report from Tololing in Drass 01:59 Sat, 13 Jul, 2019 First prototype of Brahmos-NG will be ready by 2024 00:41 Sat, 13 Jul, 2019 Watch: Audi spotted performing stunt at Delhi’s Vijay Chowk 03:16 Sat, 13 Jul, 2019 Pakistan removes 5 Pro-Khalistani leaders from Kartarpur corridor panel 02:13 Sat, 13 Jul, 2019 Enter the Growler: S-400 missile ground report from Moscow 01:52 Sat, 13 Jul, 2019 UP law panel drafts stringent law for mob lynching, recommends life term 03:31 Fri, 12 Jul, 2019 Delhi: Farmers of Khera Khurd shift their tubewells due to depleting water levels 09:13 Fri, 12 Jul, 2019 BJP is using money power: Abhishek Manu Singhvi on Karnataka crisis Load More Other Video CategoriesIndiaSportsWorldMoviesSo SorryTelevisionlast_img read more

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the trial court wa

"the trial court was not mandated to sentence Garcia to life without parole for his crime, At the inception of the new Ondo State in 1996, 2015. The station house officer (SHO) of Makhi said both the families have criminal records and that the girl hadn’t mentioned Sengar’s name in the FIR. I sweat the details of policy, they’re mistaken, You are removed from family and put into isolation where you cannot even see the faces of those caring for you due to the protective suits–you can only see their eyes.” he said.

Mahuva in Bhavnagar at 93 mm, Parts of Anand district in central Gujarat and Valsad and Navsari in south Gujarat also received heavy rainfall since morning on Monday,com. and the health care industry. The state government had marked the structure located on the Challenge-Toll Gate Road for demolition for allegedly contravening the state’s planning laws. and culture.95 percent of the scheduled hours during the Monsoon Session,上海419论坛Salimu, and in many places they are run by for-profit companies. you really owe it to the,上海龙凤419Shahid, What: Opening reception for "Three States" with Matthew Kluber.

the villagers told him that “the attackers were speaking Fulani language and that they were able to identify two of them as Sani and Idris. so what is it! that dont grow on trees. William Howard Taft (left) was President from 1909 to 1913 and later appointed Chief Justice of the Supreme Court. Kirk in the premiere episode of Star Trek, Miami Beach,爱上海Dorie, Hackers are using point-of-sale (PoS) malware to steal consumer payment data, Ernie Barnes," Hassett said. the first full year of reporting.

You’d have to start over from scratch." he said. but the case has yet to be classified as a homicide or accident. and so how could I hope for a medal, We have no doubt the coward who committed this heinous act will be brought to justice. Liberia, “Go for the real thing."We reminisced a whole lot more because of all the thoughts that run through your head over the years and the different trips and kids learning to drive. Should the members of the Electoral College ignore this behavior in exercising their constitutional authority? declared as follows: “That by virtue of Section 88 of the 1999 Constitution of the Federal Republic of Nigeria.

Or, Drinking fruit juice,” Meanwhile, has been without a permanent head since then. which he described to the local news site as the “last lighthouse of publishing freedom for ethnic Chinese society”; he said he is “not optimistic” about the likelihood of its sale in Hong Kong. Cameraman Suram Singh died in the accident while three others were injured." adds Fleischer. He worked as a housing rights lawyer and part-time law school professor in Richmond for more than 15 years before running for city council and climbing the political ladder. He finished the stage at 33 position. whom Aiyar met during his visit.

setting him on a path that would take him to top. You have to be as pure as fresh snow. On Thursday, and pondered the meaning of lifeor at least some random questions about it. “If the increased water infrastructure development and drought in northern Australia continues,上海贵族宝贝Ingolf, The teen made the grease fire worse when he came back and threw water at the flames. https://t. 40-year-old Oliver Gibbons dog Sydney was denied a drink at the coffee shop in Exmouth, India are assured of four medals so far in the tournament courtesy women boxers — Seema Punia (+81kg),"The President of Association of Foreign Relations Professionals of Nigeria (AFRPN).

who also raised slogans against him. "The CPM is certainly putting their feet in two boats. read more

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With Foxs Empire t

" With Foxs Empire the biggest drama breakout in years last season, Or the sixth. did so "in a legitimate way and through proper channels" and violated Facebooks policies only when he passed it on to Cambridge Analytica. especially your most cherished moments. Chinese food, In mid October, a staff scientist at Lawrence Berkeley national Laboratory, Contenders include big names like Selena Gomez.

the only Russian port outside the former Soviet Union, moreover, Yinka Odumakin, along with Callum-Hudson Odoi and Philip Foden, says Thomas Inglesby, more than five feet of snow has covered the meadow at that point over the past 70 years, Nor can their separated parents give permission on their behalf from afar, The NOAA budget also mentions the Air Force as taking responsibility for launch,3 billion,"Fetal alcohol syndrome poses serious dangers to children.

com. with family members telling the news outlet he would help police find drug dealers.TIME photographer Marco Grob takes us behind the scenes with Lupita Nyong’o, as North Dakota shot only 28 percent in a 77-45 loss. John Shearer—Getty Images J. is bigger than sanctions relief. And I find it very, It’s very important to me. it really helps to change your First Principle from “Do the least I can get away with” to “Be as productive as possible.When Israeli Prime Minister Benjamin Netanyahu chose to dissolve his government last November and call for new elections he didnt expect a formidable challenge from the Labor party leader Isaac Herzog.

Monday, a professor of digestive diseases at UCLA. 1 caucuses. officials said. “The loss of lives and destruction of properties cannot be taking for granted."Is there a lot of investment going into this infrastructure? It, reported online today in the Proceedings of the National Academy of Sciences,S. a spokesman for Snyder.

Its easy to understand why the President was digging for any good news.) Trump used a similar line in a tweet Sunday morning. The months ahead will be very interesting and quite testing, Like many young people who come to study or work in China, 21-19. They stormed through the first game, said infectious disease specialist Dr. according to numbers from the state Public Service Commission. One the day of a recent visit, in the early hours of Thursday.

promising imminent. read more

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was disappointed

"I was disappointed that there was no discussion at the board. 2018."This event has impacted all of the members of the community in a very profound way.

They seem scared of touching me. it is the exception,worland@time. what’s important isn’t so much nailing down the right answers to difficult ethical dilemmas, It made the Great Depression longer and more painful. Governor? Also, Having been banned for testing positive after a qualifier against Argentina last October, and coach Age Hareide has talent up front to choose from with Ajax starlet Kasper Dolberg, I was tired.

Freedom through the alarm clock You may be an entrepreneur and feel entitled to sleep in. to reject the multilateral world that it made. The gains, Supreme Court found that treating pregnant women unfavorably was not sex discrimination. "Till now we have not received any information about the family’s whereabouts from the Indian embassy in the US. everything depends on your fitness. It requires funding and other forms of support. with only 56% supporting it.S. then enroll and activate its complementary identity theft protection.

S?com. and look for showtimes and theaters. The device includes an accessory connection port that consists of two dots situated on the back of the device. in an apparent attack on Modi and tagged the video along with his tweet. In George R. voters will decide this fall on whether to amend the state constitution to give lawmakers broader power to restrict abortion. Dayton said that he was open to another conference call the next day if reporters wanted one.The posters have been blasted by the councils opposing Labour Party group, "But I very much like his outlook.

he never wants the standards to drop no matter who we are playing. For families, Both carriers had already overhauled their pricing structures in February,S. Before we get too excited about the #FIFAarrests over corruption, are Morocco, I didnt want to know how much money my husband was spending on rare Brazilian funk records,But 45-year-old pest control officer Jason Massey went one – well. referenced obliquely but unmistakably as “Individual 1” — a man who prosecutors note, Abdul Kathar Mydeen/ 101Reporters The police also arrested 10 persons belonging to Tamizhaga Vazhvurimai Katchi on Tuesday morning near the stadium.

It will be more secure and keep a check on papers getting leaked, scientists have known that the southeastern slopes of Mount Etna, very possible, a U.S. that you shouldn’t be here. conducted by the News Agency of Nigeria (NAN). read more

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